Ethanone, 2-bromo-1-pyrazinyl-

Ethanone, 2-bromo-1-pyrazinyl- - Names and Identifiers

Name	2-Bromo-1-pyrazin-2-ylethanone
Synonyms	2-(BroMoacetyl)pyrazine 2-(2-BroMoacetyl)pyrazine 2-BROMO-1-PYRAZINYL ETHANONE Ethanone, 2-bromo-1-pyrazinyl- 2-Bromo-1-pyrazin-2-ylethanone 2-BroMo-1-(2-pyrazinyl) Ethanone 2-bromo-1-(pyrazin-2-yl)ethan-1-one Ethanone, 2-bromo-1-pyrazinyl- (9CI)
CAS	132426-19-8
InChI	InChI=1/C6H5BrN2O/c7-3-6(10)5-4-8-1-2-9-5/h1-2,4H,3H2

Ethanone, 2-bromo-1-pyrazinyl- - Physico-chemical Properties

Molecular Formula	C6H5BrN2O
Molar Mass	201.02
Density	1.666±0.06 g/cm3(Predicted)
Boling Point	269.0±25.0 °C(Predicted)
Flash Point	116.461°C
Vapor Presure	0.007mmHg at 25°C
pKa	-0.91±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.581

Ethanone, 2-bromo-1-pyrazinyl- - Introduction

2-Bromo-1-(2-pyrazinyl) ethanone, chemical formula C8H7BrN2O, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-Bromo-1-(2-pyrazinyl) ethanone is white crystal or crystalline powder.
-Solubility: It dissolves in organic solvents such as ethanol, chloroform and dimethylformamide, but has poor solubility in water.
-Melting point: Its melting point is about 86-88°C.
-Molecular weight: Its molecular weight is 218.06g/mol.

Use:
-2-Bromo-1-(2-pyrazinyl) ethanone is commonly used as a pharmaceutical and pesticide intermediate. It is involved in the synthesis of various bioactive compounds, such as pyrazine drugs, coumeterone alkalophilic substances.

Preparation Method:
-2-Bromo-1-(2-pyrazinyl) ethanone can be prepared by the following methods:
1. The pyrazine is reacted with alkali metal bromide (such as potassium bromide, sodium bromide, etc.).
2. Acidify 2-pyrazinamine with acetic acid, and then react the resulting amide with acetone bromide.

Safety Information:
-2-Bromo-1-(2-pyrazinyl) ethanone is relatively safe under correct use and storage.
-It may be irritating to the skin, eyes and respiratory system, so wear protective gloves, goggles and a mask when using it.
-Avoid inhaling its powder and avoid contact with skin and eyes.
-It is recommended to use in a well-ventilated place.
-Observe relevant chemical safety practices during handling and disposal.

Last Update：2024-04-09 20:49:11